Patients w/ neutropenia (neutrophil counts <1,000 cells/mm3
). Consider Clostridium difficile
-associated diarrhea (CDAD) in all patients who present w/ diarrhea following antibiotic use; careful medical history as CDAD may occur >2 mth after antibacterial administration. Discontinue antibacterial use (not directed against Clostridium difficile
) if CDAD is suspected or confirmed. May increase risk of drug-resistant bacteria development if used in absence of a proven/strongly suspected bacterial infection or prophylaxis. Pregnancy & lactation. Childn <18 yr. Elderly ≥65 yr.