Spiriva Respimat

Spiriva Respimat Overdosage

tiotropium bromide


Boehringer Ingelheim


Full Prescribing Info
High doses of tiotropium bromide may lead to anticholinergic signs and symptoms.
However, there were no systemic anticholinergic adverse effects following a single inhaled dose of up to 340 microgram tiotropium bromide in healthy volunteers. Additionally, no relevant adverse effects, beyond dry mouth/throat and dry nasal mucosa, were observed following 14-day dosing of up to 40 microgram tiotropium solution for inhalation in healthy volunteers with the exception of pronounced reduction in salivary flow from day 7 onwards. No significant undesirable effects have been observed in four long term-studies in COPD patients with a daily dose of 10 microgram tiotropium solution for inhalation over 4-48 weeks.
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