Sucralfate - oral

Patient Medicine Information
Why do I need this medicine?
Sucralfate is used to treat conditions caused by excessive acidity in the stomach such as ulcers in the stomach or duodenum (upper portion of the small intestine) and long-term gastritis (inflammation of the stomach lining).

This medicine works by forming a coating that protects the stomach ulcers from further damage caused by stomach acids.

Sucralfate may be used to treat other conditions as decided by your doctor.

How do I take this medicine?
Take Sucralfate exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.

Take it on an empty stomach, at least 1 hour before or 2 hours after a meal. Try to take it at the same time each day.

Sucralfate is available as a tablet and oral suspension.

If you are taking an oral suspension, shake the bottle well before you take it to ensure that the liquid is evenly mixed. Use the measuring spoon or cup provided to measure your dose.

If the patient is on enteral tube feeding, Sucralfate must be given at least 1 hour before or after feeds. Always flush the tubing with water after each dose of this medicine to ensure that the full dose is taken.

The dose of this medicine will be decided by your doctor. Your doctor will advise you on the treatment timeframe depending on your condition.

Sucralfate must be taken regularly for it to be effective. Continue taking this medicine even when you feel better. Do not stop taking it unless instructed by the doctor.
What should I do if I have forgotten to take this medicine?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.

DO NOT double a dose under any circumstances.

If you often forget to take your medicine, let your doctor and pharmacist know.
What should I take note of while taking this medicine?
Inform your doctor if you have the following conditions:
  • diabetes mellitus
  • difficulty in swallowing
  • serious illness e.g. being fed by using a tube to the stomach
  • kidney disease or undergoing dialysis
Let your doctor know if you are pregnant or breastfeeding.

Be sure to check with your doctor or pharmacist before giving this medicine to the elderly. Elderly people may be more sensitive to the side effects.

For as long as you are taking Sucralfate, you may need to have regular blood tests (e.g. blood sugar or aluminium phosphate levels) to check your body’s response to the medicine. Your doctor will advise you about how often you need to have blood tests.
What side effects could I experience?
Sucralfate may cause any of the following side effects: constipation, diarrhoea, stomach wind, stomach discomfort, indigestion, dry mouth, nausea, vomiting, headache, dizziness, drowsiness, difficulty sleeping, and back pain.

If you develop rashes, breathlessness, swollen face, eyes, mouth or throat, stop taking this medicine and inform your doctor immediately. These could be signs of an allergic reaction.

Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Can I take this with other medicines?
Inform your doctor and pharmacist if you are taking any of these medicines:
  • medicines for irregular heartbeat e.g. digoxin, quinidine
  • certain antibiotics e.g. ciprofloxacin, ofloxacin, tetracycline
  • medicines that reduce stomach acid production e.g cimetidine, ranitidine
  • ketoconazole (medicine to treat fungal infection)
  • sulpiride (medicine for mood disorders)
  • levothyroxine (medicine for thyroid disease)
  • phenytoin (medicine for fits or seizures)
  • warfarin (blood-thinning medicine)
  • theophylline (asthma medicine)
  • medicines containing aluminium
This list does not include all medicines that may interact with Sucralfate.

This medicine should not be taken with antacids as antacids could reduce the effectiveness of Sucralfate. If you must take an antacid, take it at least 30 minutes before or after you have taken this medicine.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
What special dietary instructions should I follow?
Avoid alcohol.
How should I store this medicine?
Store in a cool, dry place away from the reach of children.

Do not freeze the oral suspension.

Medicines must not be used past the expiry date.
This information is independently developed by MIMS based on sucralfate - oral and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2022 MIMS. All rights reserved. Powered by
  • Apo-Sucralfate
Exclusive offer for doctors
Register for a MIMS account and receive free medical publications worth $139 a year.
Sign up for free
Already a member? Sign in