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Pain relief during labour and delivery
Adult: 10-15 mcg plus 10 ml bupivacaine 0.125% with or without epinephrine. May repeat dose twice at intervals of at least 1 hr until delivery. Max (total dose): 30 mcg.
Intravenous
Adjunct to anaesthesia with nitrous oxide and oxygen
Adult: For surgical procedures ≤8 hr: Up to 75% of the dose to be given before intubation followed by additional doses of 10-50 mcg as needed during surgery; dose may also be given by continuous or intermittent infusion. Total dose should not exceed 1 mcg/kg/hr.
Child: Given with 100% oxygen, 10-25 mcg/kg as initial dose; maintenance doses: 25-50 mcg as necessary.
Elderly: Dosage reduction may be required.
Child: Given with 100% oxygen, 10-25 mcg/kg as initial dose; maintenance doses: 25-50 mcg as necessary.
Elderly: Dosage reduction may be required.
Intravenous
Postoperative pain
Adult: Initially, 30-60 mcg. Additional doses of up to 25 mcg may be given at intervals of at least 1 hr if necessary.
Elderly: Dosage reduction may be required.
Elderly: Dosage reduction may be required.
Intravenous
Primary anaesthetic
Adult: Given with 100% oxygen, initially, 8-30 mcg/kg. For maintenance, additional doses of 0.5-10 mcg/kg may be given as necessary. Max (total dose): 30 mcg/kg.
Child: Initially, 10-25 mcg/kg, to be used with 100% oxygen. Maintenance doses of up to 25-50 mcg.
Elderly: Dosage reduction may be required.
Child: Initially, 10-25 mcg/kg, to be used with 100% oxygen. Maintenance doses of up to 25-50 mcg.
Elderly: Dosage reduction may be required.