Tetavax Special Precautions


sanofi pasteur


Full Prescribing Info
Special Precautions
If Guillain-Barré syndrome or brachial neuritis has occurred following receipt of prior vaccine containing tetanus toxoid, the decision to give any vaccine containing tetanus toxoid should be based on careful consideration of the potential benefits and possible risks. Vaccination is usually justified when primary immunizations schedules are incomplete (i.e., fewer than three doses have been received).
Do not inject by the intravascular route. Make sure the needle does not penetrate a blood vessel.
As with all injectable vaccines, appropriate medical treatment should always be readily available and supervision provided in case of an anaphylactic reaction following administration of the vaccine.
An immunosuppressive treatment or an immunodeficiency condition may induce a decrease in the immune response to the vaccine. It is therefore recommended to wait for the end of the treatment for the vaccination or to make sure that the subject is well protected. However, the vaccination of subjects with chronic immunodepression, such as HIV infection, is recommended if the underlying disease allows an antibody response, even if limited.
In order to prevent hypersensitivity reactions, avoid administering the vaccine to persons who have received a complete primary vaccination or a booster dose in the previous 5 years.
The potential risk of apnoea and the need for respiratory monitoring for 48 - 72 h should be considered when administering the primary immunization series to very premature infants (born ≤ 28 weeks of gestation) and particularly for those with a previous history of respiratory immaturity. As the benefit of vaccination is high in this group of infants, vaccination should not be withheld or delayed.
Effects on Ability to Drive and Use Machines: Not applicable.
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