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Indications and Dosage
Ophthalmic
Production of cycloplegia Adult: Instill 1-2 drops of a 1% solution repeated after 5 minutes. An additional drop may be admin after 20-30 minutes for prolonged effect. Ophthalmic Production of mydriasis Adult: Instill 1-2 drops of a 0.5% solution 15-20 minutes before examination.
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Contraindications
Hypersensitivity. Narrow-angle glaucoma or shallow anterior chamber.
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Special Precautions
Elderly, children, pregnancy. Hypertension, hyperthyroidism, DM, cardiac disorders. To reduce systemic absorption, press on the lacrimal sac for 1-2 minutes following instillation. Do not drive or engage in hazardous activities and protect eyes from bright illumination when pupils are dilated. May fail to produce adequate cycloplegia in children.
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Adverse Reactions
Increased intraocular pressure, transient stinging, dry mouth, blurred vision, photophobia, tachycardia, headache, superficial punctate keratitis, systemic anticholinergic effects, severe CNS disturbances in children (rare).
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Ophth: C
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Drug Interactions
May antagonise effects of ophthalmic carbachol, pilocarpine, or cholinesterase inhibitors.
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Action
Description: Tropicamide is a tertiary amine antimuscarinic which causes relaxation of the sphincter muscle of the iris resulting in pupillary dilatation. It also causes paralysis of the ciliary muscle leading to loss of accommodation.
Onset: Mydriasis: 20-40 min; cycloplegia: 30 min. Duration: Mydriasis: 6 hrs; cycloplegia: 6 hrs. |
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Storage
Store between 15-30°C. Do not refrigerate.
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MIMS Class
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