History of allergic reaction to pain-killers. Not to be taken w/ alcohol; other paracetamol-containing medicines. Concomitant use w/ warfarin or similar blood thinners. Underwt or malnourished. Patients regularly drinking alcohol. Discontinue treatment if the patient experiences allergic reactions; potential serious skin reactions; previously experienced breathing problems w/ aspirin or NSAIDs; nausea, sudden wt loss, appetite loss & yellowing of eyes & skin; unexplained bruising or bleeding; mouth ulcers. Risk for metabolic acidosis may be increased if the patient has a severe infection. Liver or kidney disease; history of liver or kidney disease. Pregnancy & lactation. Not recommended for childn <12 yr.