UFT

UFT

tegafur + uracil

Manufacturer:

Taiho

Distributor:

Pharmaforte
Concise Prescribing Info
Contents
Tegafur 100 mg, uracil 224 mg
Indications/Uses
Remission of subjective & objective symptoms in cancers of the head & neck, gastric, colorectal, hepatocellular, gallbladder or bile duct, pancreatic, lung, breast, bladder, prostate & uterine cervical.
Dosage/Direction for Use
300-600 mg in 2 or 3 divided doses daily. Uterine cervical cancer 600 mg in 2-3 divided doses daily.
Administration
Should be taken on an empty stomach: Take 1 hr before or after meals.
Contraindications
Concomitant use w/ tegafur, gimeracil & oteracil K combination product or w/in 7 days after w/drawal of UFT. Pregnancy & lactation.
Special Precautions
Bone marrow depression, hepatic or renal disorder, infectious disease, heart disease, GI ulcer or haemorrhage, abnormal glucose tolerance, varicella, dihydropyrimidine dehydrogenase deficiency. Monitor haematological, hepatic & renal functions closely. Avoid dehydration; appearance or aggravation of infection or bleeding tendency. Acute leukaemia or myelodysplastic syndrome. Childn. Elderly.
Adverse Reactions
Blood dyscrasias, severe hepatic disorder, hepatic cirrhosis, severe diarrhea, severe enteritis, severe psychoneurologic disorder, angina pectoris, MI, arrhythmia, acute renal failure, nephrotic syndrome, anosmia, interstitial pneumonia, acute pancreatitis, severe stomatitis, GI ulcer & haemorrhage, Stevens-Johnson & Lyell's syndrome.
Drug Interactions
Phenytoin, warfarin K, other antineoplastic agents or radiation therapy.
ATC Classification
L01BC53 - tegafur, combinations ; Belongs to the class of antimetabolites, pyrimidine analogues. Used in the treatment of cancer.
Presentation/Packing
Form
UFT cap
Packing/Price
12 × 10's
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