40% of the dose of oxazaphosphorine (rounded to the nearest whole tab) to be taken at -2, 2 & 6 hr after oxazaphosphorine dosing. If Uromitexan is given by IV at 1st instance, the oral dose at -2 hr should be replaced by IV at 0 hr. Inj Adult
Usually given at 20% of the dose of oxazaphosphorine at 0, 4 & 8 hr after administration of oxazaphosphorine. Childn
Dose given at greater frequency (eg, 6 times) & at shorter intervals (eg, 3 hr). W/ very high-dose cytostatic therapy, total dose can be increased to 120% of the oxazaphosphorine dose.