Fe deficiency anaemia where there is a clinical need for a rapid Fe supply; in patients who cannot tolerate oral Fe therapy or are noncompliant; where oral Fe prep are ineffective (eg, active inflammatory bowel disease).
IV Individualized dosage. Inj Total single daily dose: Max 200 mg, given not more than 3 times a wk. Infusion Total single daily dose: Max 500 mg, given not more than once a wk.
Potentially fatal allergic or anaphylactoid reactions (patients w/ history of asthma, eczema, other atopic allergies or allergic reactions to other parenteral Fe prep have higher risk). Observe patients for adverse events for at least 30 min following each inj. Patients w/ liver dysfunction. Carefully monitor Fe status to avoid Fe overload. Patients w/ acute or chronic infection. Avoid paravenous leakage; immediately stop administration when pain, inflammation, tissue necrosis & brown skin discoloration occur. Lactation.
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