Vindesine - intravenous


Patient Medicine Information
Why do I need this medicine?
Vindesine is used to treat cancer of the skin and breast in individuals who did not respond to prior therapy.

This medicine may also be used to treat certain types of blood cancer.
How do I use this medicine?
Vindesine injection is to be given intravenously (into the vein). It is delivered directly into the bloodstream via the blood vessel.

Your doctor or nurse will administer the injection for you.

The dose of this medicine will be decided by your doctor. Your doctor will advise you on the treatment timeframe depending on the type and severity of your condition.
What should I do if I have forgotten to use this medicine?
Ensure that you keep all appointments with your doctor so that you do not miss any doses. Your doctor also needs to regularly monitor your response to Vindesine.

If you miss an appointment or miss an injection, alert your doctor or nurse. A replacement appointment or injection should be given as soon as possible.
When should I not use this medicine?
Alert your doctor if you have the following conditions:
  • demyelinating form of Charcot-Marie-Tooth syndrome (inherited disorder that causes nerve damage)
  • decreased blood granulocytes (a type of white blood cell)
  • lower than normal platelet counts in the blood
  • bacterial infection
as Vindesine may not be suitable for you.
What should I take note of while using this medicine?
Inform your doctor if you have the following conditions:
  • neuromuscular disease
  • liver disease
Let your doctor know if you are pregnant or breastfeeding.

Why is it important to keep my appointments with the doctor?

Keep your appointments with your doctor. Your doctor needs to monitor your condition and check your response to the medication regularly.
  • Routine tests (e.g. blood test, liver function) may be done while you are being treated with this medicine. Your doctor will advise you about how often you need to have these tests.
  • Regular monitoring of signs of infusion site reaction and infection may also be needed.
What side effects could I experience?
Vindesine may cause any of the following side effects: headache, constipation, stomach pain, diarrhoea, loss of reflexes, fever, joint pain, rashes and hair loss.

This medicine may cause the level of your red blood cells, white blood cells and platelets to drop.

Red blood cells carry oxygen around your body. A fall in the level of red blood cells may make you feel tired and worn out.

White blood cells help your body to fight infections. A fall in the level of your white blood cells may put you at higher risk for infections, such as coughs, colds and flu, which may lead to more serious infections. Avoid crowded places and people who are sick. Alert your doctor if you have a fever, or a cough or flu that does not go away.

Platelets help your blood to clot when there is a cut in the skin. A fall in the level of your platelets may put you at risk of bleeding more than usual. Do not take part in activities where you may fall or get injured, such as contact sports. Alert your doctor if you get any unusual bruising (large bruises or several bruises, especially if the bruises appeared on their own) or bleeding that takes a long time to stop (for example, too much bleeding when you floss or brush your teeth).

Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Can I use this with other medicines?
Inform your doctor and pharmacist if you are taking or using any of these medicines:
  • other medicines for cancer e.g. mitomycin
  • phenytoin (medicine for epilepsy)
This list does not include all medicines that may interact with Vindesine.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
What special dietary instructions should I follow?
Avoid alcohol.
How should I store this medicine?
Store unopened vial in the refrigerator, between 2-8°C.

Medicines must not be used past the expiry date.

As this is a cancer medicine, always return any unused or expired vial to the clinic, hospital, or pharmacy for disposal. Do not throw it away in the household waste.
This information is independently developed by MIMS based on vindesine - intravenous and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by MIMS.com
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