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Add-on orforglipron improves outcomes in T2D patients on insulin glargine

Daily treatment with oral orforglipron, when added to titrated insulin glargine, has been shown to be beneficial in individuals with inadequately controlled type 2 diabetes (T2D) in the phase 3 ACHIEVE-5 trial.

Add-on orforglipron improves outcomes in T2D patients on insulin glargine

6 hours ago

Tirzepatide superior to ICC in metformin-resistant T2D

7 hours ago

Treatment with tirzepatide yields robust reductions in HbA1c, weight, and waist circumference in patients with early type 2 diabetes (T2D) uncontrolled with metformin, reports a study.

Tirzepatide superior to ICC in metformin-resistant T2D

7 hours ago

COVID-19 vaccine improves survival outcomes in cancer patients on ICI therapy

8 hours ago by

Vaccination against COVID-19 provides survival benefits to cancer patients receiving immune checkpoint inhibitors (ICIs), as shown in a recent study.

COVID-19 vaccine improves survival outcomes in cancer patients on ICI therapy

8 hours ago

Change in supine-to-standing SBP predicts mortality in females

9 hours ago

In healthy females, the change in supine-to-standing systolic blood pressure (SBP) is associated with mortality, regardless of traditional risk factors and antihypertensive medications, suggests a study.

Change in supine-to-standing SBP predicts mortality in females

9 hours ago

Sublingual cyclobenzaprine fares well in fibromyalgia

10 hours ago by

Findings from the phase III RESILIENT study show that a sublingual formulation of cyclobenzaprine (CBP SL) may benefit individuals with fibromyalgia.

Sublingual cyclobenzaprine fares well in fibromyalgia

10 hours ago

Adjuvant nivolumab confers no DFS benefit in resected NSCLC

14 hours ago

In the treatment of patients with resected non–small cell lung cancer (NSCLC) without sensitizing EGFR and ALK alterations, adjuvant nivolumab does not appear to yield improvements in disease-free survival (DFS) when given after planned adjuvant chemotherapy and/or radiotherapy, according to a phase 3 study.

Adjuvant nivolumab confers no DFS benefit in resected NSCLC

14 hours ago

Which combo regimens are better tolerated for HTN?

17 hours ago by

In a network meta-analysis of discontinuation of blood-pressure (BP)-lowering medications due to adverse effects (AEs), the best-tolerated treatment was a combination of an angiotensin receptor blocker (ARB) and a calcium channel blocker (CCB), with four of the top five best-tolerated regimens containing ARBs.

Which combo regimens are better tolerated for HTN?

17 hours ago

Antibiotic resistance genes found in newborn stool hours after birth

18 hours ago by

Antibiotic resistance genes (ARGs)—DNA segments that enable bacterial survival in the presence of antibiotics— can be detected in newborns’ meconium shortly after birth, as shown in a study presented at ESCMID Global 2026.

Antibiotic resistance genes found in newborn stool hours after birth

18 hours ago

VISTAS: Volixibat alleviates cholestatic itch in PSC

a day ago by

The investigational ileal bile acid transporter (IBAT) inhibitor volixibat provides rapid and sustained improvement in pruritus in patients with primary sclerosing cholangitis, according to the topline results of the VISTAS study.

VISTAS: Volixibat alleviates cholestatic itch in PSC

a day ago

BAT offers modest BP-lowering effect in resistant hypertension

a day ago

Home blood pressure (BP) measurements have increased significantly following baroreflex activation therapy (BAT) deactivation, even after multiannual therapy, reports a study.

BAT offers modest BP-lowering effect in resistant hypertension

a day ago

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Add-on orforglipron improves outcomes in T2D patients on insulin glargine

Add-on orforglipron improves outcomes in T2D patients on insulin glargine

Tirzepatide superior to ICC in metformin-resistant T2D

Tirzepatide superior to ICC in metformin-resistant T2D

COVID-19 vaccine improves survival outcomes in cancer patients on ICI therapy

COVID-19 vaccine improves survival outcomes in cancer patients on ICI therapy

Change in supine-to-standing SBP predicts mortality in females

Change in supine-to-standing SBP predicts mortality in females

Sublingual cyclobenzaprine fares well in fibromyalgia

Sublingual cyclobenzaprine fares well in fibromyalgia

Adjuvant nivolumab confers no DFS benefit in resected NSCLC

Adjuvant nivolumab confers no DFS benefit in resected NSCLC

Which combo regimens are better tolerated for HTN?

Which combo regimens are better tolerated for HTN?

Antibiotic resistance genes found in newborn stool hours after birth

Antibiotic resistance genes found in newborn stool hours after birth

VISTAS: Volixibat alleviates cholestatic itch in PSC

VISTAS: Volixibat alleviates cholestatic itch in PSC

BAT offers modest BP-lowering effect in resistant hypertension

BAT offers modest BP-lowering effect in resistant hypertension