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Physical activity, exercise guidelines crucial for people with IBD

30 May 2026

A recent study suggests the need for tailored guidelines for physical activity (PA) or exercise among individuals with inflammatory bowel disease (IBD).

Physical activity, exercise guidelines crucial for people with IBD

30 May 2026

Sleep-wake cycle measures may flag dementia risk

30 May 2026

Accelerometer-derived sleep-wake cycle measures are associated with dementia risk, modestly improving the accuracy of a dementia prediction model comprising established risk factors, a study has shown.

Sleep-wake cycle measures may flag dementia risk

30 May 2026

Heart failure more strongly associated with stroke in young vs older patients with AF

29 May 2026

Heart failure (HF) shows an age-dependent association with ischaemic stroke in patients with atrial fibrillation (AF), such that the association is more pronounced in young than older patients, as shown in the Finnish Anticoagulation in Atrial Fibrillation study.

Heart failure more strongly associated with stroke in young vs older patients with AF

29 May 2026

Weight loss makes no difference in older patients with overweight and persistent AF

29 May 2026 by

In older patients with overweight and persistent atrial fibrillation (AF) referred for direct current cardioversion, an 8-month structured dietary weight loss and behavioural support program leads to a significant reduction in weight without inducing functional decline. However, this metabolic benefit does not translate into improvements in AF outcomes, according to the LOSE-AF trial.

Weight loss makes no difference in older patients with overweight and persistent AF

29 May 2026

Simenafil shows potential as erectile dysfunction treatment

29 May 2026

The selective phosphodiesterase-5 inhibitor (PDE5i) simenafil demonstrates efficacy and good tolerability among men suffering from erectile dysfunction (ED), reports a phase II study.

Simenafil shows potential as erectile dysfunction treatment

29 May 2026

Diet, exercise help improve erectile function

29 May 2026 by

Adult men with erectile dysfunction may benefit from diet- and exercise-based interventions, which in a recent study have shown to yield modest but significant improvements in erectile function.

Diet, exercise help improve erectile function

29 May 2026

HIV tied to poor outcomes, death in patients with variceal GI bleeding

29 May 2026

HIV-positive patients with variceal upper gastrointestinal bleeding (VUGIB) may experience worse clinical outcomes and poor survival, according to a study.

HIV tied to poor outcomes, death in patients with variceal GI bleeding

29 May 2026

96-week PULSAR data support aflibercept 8 mg for nAMD

29 May 2026 by

Updated results from the phase III PULSAR trial show that intravitreal (IVT) aflibercept 8 mg, when administered at extended dosing intervals of up to 20 weeks, led to visual gains and anatomic improvements comparable to the 2-mg dose, with no new safety concerns over 96 weeks, in treatment-naïve individuals with neovascular age-related macular degeneration (nAMD).

96-week PULSAR data support aflibercept 8 mg for nAMD

29 May 2026

Depression linked to earlier treatment intensification in T2D

29 May 2026

For individuals with type 2 diabetes (T2D) who are initiating oral glucose-lowering monotherapy, a history of clinically diagnosed depression is associated with earlier treatment intensification, such as adding medication or switching to a new drug class, and insulin initiation, as shown in a retrospective study.

Depression linked to earlier treatment intensification in T2D

29 May 2026

Addressing the vaping epidemic: Policy and clinical observations to facilitate cessation

29 May 2026

Vaping has emerged as a significant public health concern, with the WHO estimating over 100 million users globally in 2025, including approximately 15 million adolescents. Misleading marketing and social media advertisements have perpetuated misperceptions about the health risks of vaping, driving uptake particularly among adolescents and young adults. This paper reviews the current evidence, regulatory landscape, and clinical guidance, highlighting that regulatory interventions alone are insufficient, as the heterogeneity of regulatory environments across countries limits the applicability of blanket recommendations. A multipronged approach encompassing expanded pharmacotherapy options is needed. While no standardized vaping cessation guidelines exist, several countries are extrapolating from smoking cessation frameworks and expediting pharmacotherapy approvals, recognizing the urgency of addressing this growing epidemic.

Addressing the vaping epidemic: Policy and clinical observations to facilitate cessation

29 May 2026

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Physical activity, exercise guidelines crucial for people with IBD

Physical activity, exercise guidelines crucial for people with IBD

Sleep-wake cycle measures may flag dementia risk

Sleep-wake cycle measures may flag dementia risk

Heart failure more strongly associated with stroke in young vs older patients with AF

Heart failure more strongly associated with stroke in young vs older patients with AF

Weight loss makes no difference in older patients with overweight and persistent AF

Weight loss makes no difference in older patients with overweight and persistent AF

Simenafil shows potential as erectile dysfunction treatment

Simenafil shows potential as erectile dysfunction treatment

Diet, exercise help improve erectile function

Diet, exercise help improve erectile function

HIV tied to poor outcomes, death in patients with variceal GI bleeding

HIV tied to poor outcomes, death in patients with variceal GI bleeding

96-week PULSAR data support aflibercept 8 mg for nAMD

96-week PULSAR data support aflibercept 8 mg for nAMD

Depression linked to earlier treatment intensification in T2D

Depression linked to earlier treatment intensification in T2D

Addressing the vaping epidemic: Policy and clinical observations to facilitate cessation

Addressing the vaping epidemic: Policy and clinical observations to facilitate cessation