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INTRA-ABDOMINAL INFECTIONS
Treatment Guideline Chart
Intra-abdominal infections (IAI) occur due to disruption of the normal anatomic barrier.
Hollow viscera is where common disruptions occur, which allows intraluminal bacteria to invade and proliferate in the usually sterile area (ie peritoneal cavity or retroperitoneum).
Community-acquired IAI is usually secondary to gastroduodenal perforation, ascending cholangitis, cholecystitis, appendicitis, colon diverticulitis with or without perforation, or pancreatitis.
Healthcare-associated IAI is usually secondary to leak or perforations from anastomosis or abscess from surgical site and/or wound infections.

Intra-Abdominal Infections References

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  2. Solomkin JS, Mazuski JE, Baron EJ, et al; Infectious Diseases Society of America. Guidelines for the selection of anti-infective agents for complicated intra-abdominal infections. Clin Infect Dis. 2003 Oct;37(8):997-1005. PMID: 14523762
  3. Ball CG, Hansen G, Harding GK, et al. Canadian practice guidelines for surgical intra-abdominal infections. Can J Infect Dis Med Microbiol. 2010;21(1):011-37. Accessed 01 Mar 2011. PMID: 21358883
  4. File TM. New guidelines for the management of complicated intra-abdominal infections. Infect Dis Clin Pract. 2010;18:195-197
  5. Infectious Diseases Society of Taiwan; Taiwan Surgical Society of Gastroenterology; Medical Foundation in Memory of Dr. Deh-Lin Cheng; Foundation of Professor Wei-Chuan Hsieh for Infectious Diseases Research and Education; CY Lee’s Research Foundation for Pediatric Infectious Diseases and Vaccines. Guidelines for antimicrobial therapy of intra-abdominal infections in adults. J Microbiol Immunol Infect. 2008 Jun;41(3):279-281. http://pha-bj.org. Accessed 14 Feb 2011. PMID: 18629426
  6. Malangoni MA. Contributions to the management of intra-abdominal infections. Am J Surg. 2005 Aug;190(2):255-259. PMID: 16023441
  7. Laterre PF, Colardyn F, Delmée M, et al. Antimicrobial therapy for intra-abdominal infections: guidelines from the Infectious Disease Advisory Board (IDAB). Acta Chir Belg. 2006 Feb;106(1):2-21. http://www.belsurg.org. Accessed 14 Feb 2011. PMID: 16612906
  8. Marshall JC. Intra-abdominal infections. Microbes Infect. 2004 Sep;6(11):1015-1025. PMID: 15345234
  9. Mazuski JE, Sawyer RG, Nathens AB, et al. The Surgical Infection Society guidelines on antimicrobial therapy for intra-abdominal infections: an executive summary. Surg Infect (Larchmt). 2002;3(3):161-173. PMID: 12542922
  10. Pieracci FM, Barie PS. Intra-abdominal infections. Curr opin Crit Care. 2007 Aug;13(4):440-449. PMID: 17599016
  11. Sartelli M, Viale P, Koike K, et al. 2013 WSES guidelines for management of intra-abdominal infections. World J Emerg Surg. 2013 Jan;8(1):3. doi: 10.1186/1749-7922-8-3. Accessed 06 Sep 2013. PMID: 23294512
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  13. Solomkin JS, Mazuski JE, Bradley JS, et al. Diagnosis and management of complicated intra-abdominal infection in adults and children: guidelines by the Surgical Infection Society and Infectious Diseases Society of America. Clin Infect Dis. 2010 Jan;50(2):133-164. http://www.ncbi.nlm.nih.gov/pubmed/20034345. PMID: 20034345
  14. Weigelt JA. Empiric treatment options in the management of complicated intra-abdominal infections. Cleve Clin J Med. 2007 Aug;74(Suppl 4):S29-S37. Accessed 15 Feb 2011. PMID: 17847176
  15. Finch R, Niederman MS. Moxifloxacin: 10 years of clinical experience. UNI-MED Science. 1st ed. Bremen- London-Boston: UNI-MED Verlag AG; 2011
  16. MedWormhttp://www.medworm.com/rss/index.php/Gastroenterology/17/http://www.medworm.com/rss/medicalfeeds/specialities/Gastroenterology.xml
  17. MedWormhttp://www.medworm.com/rss/index.php/Pediatrics/33/http://www.medworm.com/rss/medicalfeeds/specialities/Pediatrics.xml
  18. Kurup A, Liau KH, Ren J, et al. Antibiotic management of complicated intra-abdominal infections in adults: the Asian perspective. Annals of Medicine and Surgery. 2014 Sep;3(3):85-91. http://dx.doi.org/10.1016/j.amsu.2014.06.005. Accessed 20 Oct 2014.
  19. Montravers P, Dupont H, Leone M et al. Guidelines for management of intra-abdominal infections. Anaesth Crit Care Pain Med. 2015 Apr;34(2):117-130. doi: 10.1016/j.accpm.2015.03.005. PMID: 25922057
  20. Barshak MB. Antimicrobial approach to intra-abdominal infections in adults. UpToDate. https://www.uptodate.com. 25 Jun 2020.
  21. Sartelli M, Chichom-Mefire A, Labricciosa FM, et al. The management of intra-abdominal infections from a global perspective: 2017 WSES guidelines for management of intra-abdominal infections. World J Emerg Surg. 2017 Jul 10;12:29. doi: 10.1186/s13017-017-0141-6. PMID: 28702076
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