Medication-related osteonecrosis of the jaw (MRONJ), a major side effect of using bone-modifying agents (BMA) for cancer or osteoporosis, normally manifests intraorally. However, some patients may have an extraoral manifestation of erythematous swelling or fistulas localized to the jaw area, according to a recent study.
Unique features characterize the occurrence of heat-related illnesses, such as cramps, exhaustion, and stroke, among patients admitted to the emergency department (ED) of Singapore General Hospital, reports a recent study.
Combination treatment with sacubitril and valsartan appears to be no better than ramipril in reducing the risk of cardiovascular death and heart failure (HF) in patients with acute myocardial infarction (AMI) complicated by left ventricular dysfunction, regardless of AMI type, reveals a study.
Adding lutetium-177 (177Lu)–Dotatate radioligand therapy (RLT) to long-acting octreotide as first-line therapy significantly improves progression-free survival (PFS) in patients with newly diagnosed somatostatin receptor-positive (SSTR+), grade 2 and 3 (G2 and G3), well-differentiated gastroenteropancreatic neuroendocrine tumours (GEP-NETs) compared with high-dose long-acting octreotide alone, according to the NETTER-2 trial presented at ASCO GI 2024.
Treatment with belzutifan helps patients with previously treated advanced renal cell carcinoma (RCC) achieve better disease-specific symptoms and quality of life (QoL) compared with everolimus, according to the patient-reported outcome (PRO) data from the phase III LITESPARK-005 trial.
Several interventions for reducing physician burnout result in significant numerical improvements in some domains, but such improvements fall short of providing meaningful changes in clinical burnout, according to the results of a meta-analysis.