Known hypersensitivity to risedronate sodium or to any of the excipients of Actonel; hypocalcaemia (a low blood calcium level) (see Warnings); severe renal impairment (creatinine clearance <30 mL/min).
Use in pregnancy & lactation: There are no adequate data from the use of risedronate sodium in pregnant women. Studies in animals have shown reproductive toxicity (see Toxicology: Preclinical Safety Data under Actions). The potential risk for humans is unknown.
Actonel must not be used during pregnancy or by breastfeeding women.