Use in Pregnancy: There are no adequate data on the use of imatinib in pregnant women. Studies in animals have however shown reproductive toxicity (see Pharmacology: Toxicology: Preclinical safety data under Actions) and the potential risk for the foetus is unknown. Imatinib should not be used during pregnancy unless clearly necessary. If it is used during pregnancy, the patient must be informed of the potential risk to the foetus. Women of childbearing potential must be advised to use effective contraception during treatment.
Use in Lactation: There is limited information on imatinib distribution on human milk. Since the effects of low-dose exposure of the infant to imatinib are unknown, woman taking imatinib should not breast-feed.