Amarax 2

Amarax 2

glimepiride

Manufacturer:

Charoon Bhesaj

Distributor:

Charoon Bhesaj
Concise Prescribing Info
Contents
Glimepiride
Indications/Uses
Management of type 2 DM (NIDDM) as an adjunct to diet & exercise to lower blood glucose. In combination w/ metformin or insulin in patients whose hyperglycemia cannot be controlled by diet & exercise in conjunction w/ a single oral hypoglycemic agent.
Dosage/Direction for Use
Initially 1-2 mg once daily. Maintenance dose: 1-4 mg once daily, may be increased in 2-mg increments at 1-2 wk intervals after a dose of 2 mg once daily. Max dose: 8 mg once daily. In combination w/ insulin Initially 8 mg once daily.
Administration
Should be taken with food: Take immediately before or during breakfast, or the 1st main meal of the day. Do not skip meals.
Contraindications
Hypersensitivity to glimepiride or sulfonamides. Diabetic ketoacidosis.
Special Precautions
Severe hypoglycemia. Renal & hepatic impairment. Malnourished patients. Regularly monitor glucose levels in blood & urine. Patients w/ G6PD & rare hereditary problems of galactose intolerance. Pregnancy & lactation. Elderly. Childn. 
Adverse Reactions
Dizziness, headache, hypoglycemia, nausea & weakness.
Drug Interactions
Potentiation of blood sugar-lowering effect by insulin, oral antidiabetics, ACE inhibitors, allopurinol, anabolic steroids & male sex hormones, chloramphenicol, coumarin derivatives, cyclophosphamide, disopyramide, fenfluramine, fenyramidol, fibrates, fluoxetine, guanethidine, ifosfamide, MAOIs, miconazole, para-aminosalicylic acid, quinolones, salicylates, sulfinpyrazone, sulfonamides, tetracyclines, tritoqualine, trofosfamide. Raised blood sugar levels w/ acetazolamide, barbiturates, corticosteroids, diazoxide, diuretics, epinephrine & other sympathomimetic agents, glucagons, laxatives (after protracted use), nicotinic acid (in high dose), estrogens & progestrogens, phenothiazines, phenytoin, rifampicin, thyroid hormones.
MIMS Class
ATC Classification
A10BB12 - glimepiride ; Belongs to the class of sulfonylureas. Used in the treatment of diabetes.
Presentation/Packing
Form
Amarax 2 tab 2 mg
Packing/Price
10 × 10's
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