The most common side effects are headache and edema.
Doses related side effects from amlodipine are edema, dizziness, flushing, and palpitation whereas unclear doses related side effects are headache, fatigue, nausea, abdominal pain and somnolence.
Rare side effects that a causal relationship is uncertain as follows: Cardiovascular: Arrhythmia (including ventricular tachycardia and atrial fibrillation), bradycardia, chest pain, hypotension, peripheral ischemia, syncope, tachycardia, postural dizziness, postural hypotension, vasculitis.
Central and peripheral nervous system: Hypoesthesia, peripheral neuropathy, paresthesia, tremor, vertigo.
Gastrointestinal: Anorexia, constipation, dyspepsia, dysphagia, diarrhea, flatulence, pancreatitis, vomiting, gingival hyperplasia.
General: Allergic reaction, asthenia, back pain, hot flushes, malaise, pain, rigors, weight gain, weight decrease.
Musculoskeletal system: Arthralgia, arthrosis, muscle cramps, myalgia.
Psychiatric: Sexual dysfunction (male and female), insomnia, nervousness, depression, abnormal dreams, anxiety, depersonalization.
Respiratory system: Dyspnea, epistaxis.
Skin and appendages: Angioedema, erythema multiforme, pruritus, rash, rash erythematous, rash maculopapular.
Special senses: Abnormal vision, conjunctivitis, diplopia, eye pain, tinnitus.
Urinary system: Micturition frequency, micturition disorder, nocturia.
Autonomic nervous system: Dry mouth, sweating increased.
Metabolic and nutritional: Hyperglycemia, thirst.
Hemapoietic: Leucopenia, purpura, thrombocytopenia.
Very rare side effects are cardiac failure, pulse irregularity, extrasystoles, skin discoloration, urticaria, skin dryness, alopecia, dermatitis, muscle weakness, twitching, ataxia, hypertonia, migraine, cold and clammy skin, apathy, agitation, amnesia, gastritis, increased appetite, loose stools, coughing, rhinitis, dysuria, polyuria, parosmia, taste perversion, abnormal visual accomodation, and xerophthalmia.