Each litre of solution contains L-leucine 13 g, L-isoleucine 8 g, L-lysine acetate 12 g (equivalent to L-lysine 8.51 g), L-methionine 3.12 g, L-phenylalanine 3.75 g, L-threonine 4.4 g, L-tryptophan 2.01 g, L-valine 9 g, arginine 7.5 g, L-histidine 4.76 g, glycine 4.15 g, L-taurine 0.4 g, L-serine 7.67 g, L-alanine 9.3 g, L-proline 9.71 g, N-acetyl-L-tyrosine 5.176 g (equivalent to L-tyrosine 4.2 g), N-acetyl-L-cysteine 0.7 g (equivalent to L-cystenine 0.52 g), L-malic acid 2.62 g. Total amino acids: 100 g/L. Total nitrogen content: 14.9 g/L. Titration acidity: 25-45 mmol NaOH/L. pH value: 5.5-6. Theoretical osmolarity: 885 mOsmol/L.
For partial parenteral nutrition in premature infants, babies and small children.
Together with corresponding amounts of electrolytes, carbohydrates and fat emulsions as energy donors, the solution may serve for total parenteral nutrition.
Maximum Infusion Rate: Up to 0.1 g amino acids/kg body weight/hr = 1 mL/kg body weight/hr. Maximum Daily Dosage: 1st year of living: 1.5-2.5 g amino acids/kg body weight; 2nd year of living: 1.5 g amino acids/kg body weight; 3rd-5th year of living: 1.5 g amino acids/kg body weight ; 6th-10th year of living: 1 g amino acids/kg body weight; 11th-14th year of living: 1 g amino acids/kg body weight.
The solution is administered as long as parenteral nutrition is required.
Administration: For IV infusion.
Note: Too rapid infusion may result in renal losses causing amino acid imbalance. Electrolytes should be administered according to the requirements.
Disturbances in amino acid metabolism, acidosis, hyperhydration, hypokalemia.
Patients with insufficient renal or hepatic function require an individual dosage.
Attention in case of hyponatremia.
When administering amino acids as part of the parenteral nutrition of premature infants, babies and small children, the following laboratory parameters must be regularly checked: Urea-nitrogen acid-base balance, serum ionogram, liver enzymes, lipid levels (where fat emulsions are used), water balance and if necessary serum amino acid levels.
Because of the increased risk of microbiological contaminations and incompatibilities, amino acid solutions should not be mixed with other drugs.
Note: The addition of drugs may alter the chemical and physical properties of the solution and may therefore give rise to toxic reaction.
Should it nevertheless become necessary to add drugs to Aminoven Infant 10%, it is imperative to ensure sterility, complete mixing and compatibility. The same applies for the adding of lipid emulsions, trace elements and vitamins for complete parenteral nutrition mixtures.
Use only clear solutions and undamaged containers.
Store not above 25°C. Protect from light.
B05BA01 - amino acids ; Belongs to the class of solutions for parenteral nutrition used in I.V. solutions.