Ampine-5 Special Precautions





Prosp Pharma
Full Prescribing Info
Special Precautions
Use in patients with congestive heart failure: Amlodipine should be used with caution in patient with congestive heart failure because of the slight risk of negative inotropic effect.
Use in patients with hepatic function impairment: Clearance of amlodipine may be reduced since it undergoes extensive hepatic metabolism, elimination half-life may be prolonged. The drug should therefore be administered with caution in these patients.
Use in Elderly: The half-life of amlodipine may be increased in the elderly. These patients may be more sensitive to the hypotensive effects of amlodipine and may require a lower initial dose.
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