Hypertension: The usual initial antihypertensive oral dose of amlodipine is 5 mg once daily with a maximum dose of 10 mg once daily. The elderly or patients with hepatic insufficiency may be started on 2.5 mg once daily, and this dose may be used when adding amlodipine to other antihypertensive therapy. Dosage should be adjusted according to each patient's need. The titration should proceed over 7 to 14 days so that the physician can fully assess the patient's response to each dose level.
Chronic stable or vasospastic angina: The recommended dose is 5 to 10 mg with the lower dose suggested in the elderly and in patients with hepatic insufficiency.
Administration: AMVAS 10 is administered orally once daily without regard to meals.