Adults: Repeated intravenous injection: Initial dosage: Labetalol hydrochloride injection should be given in a dose of 20 mg labetalol hydrochloride (which corresponds to 0.25 mg/kg for an 80 kg patient) by slow intravenous injection over at 2 minute period.
Maintenance dosage: Additional injections of 40 or 80 mg can be given at 10 minute intervals until a desired supine blood pressure is achieved or a total of 300 mg of labetalol hydrochloride has been injected. The maximum effect usually occurs within 5 minutes of each injection.
Slow continuous infusion: 500-200 mg; A total dose of up to 300 mg may be required in some patients at a rate of 2 mg/min. The rate of infusion of a diluted solution may be adjusted according the blood pressure response at the discretion of health care provider.
Avexa is intended for intravenous use.