Undesirable effects of Berodual/Forte are nervousness, dry mouth, headache, dizziness and fine tremor of skeletal muscles. Tachycardia, increased heart rate and palpitations may occur. Gastrointestinal motility disturbances (eg, vomiting, constipation, diarrhea) and urinary retention albeit reversible have been reported.
Ocular side effects (including accommodation disturbances and glaucoma) may occur (see Precautions). Skin reactions or allergic-type reactions eg, skin rash, angioedema of the tongue, lips and face, urticaria, laryngospasm and anaphylactic reactions have been reported.
Potentially serious hypokalemia may result from β2-agonist therapy.
As with other β-agonist-containing products, nausea, vomiting, sweating, weakness and myalgia/muscle cramps may occur.
Decrease in diastolic blood pressure and increase in systolic blood pressure have been observed. Arrhythmias (particularly after higher doses), atrial fibrillation and supraventricular tachycardia may occur.
In individual cases, psychological alterations have been reported under inhalational therapy with β-agonist-containing products.
As with use of other inhalation therapy, cough, local irritation (eg, pharyngitis, throat irritation) and inhalation-induced bronchospasm have been reported.