Betaloc Zok

Betaloc Zok Dosage/Direction for Use

metoprolol

Manufacturer:

AstraZeneca

Distributor:

DKSH
Full Prescribing Info
Dosage/Direction for Use
Betaloc ZOK is intended for once daily treatment and is preferably taken in the morning. The Betaloc ZOK tablet should be swallowed with liquid. The tablets and the divided halves should not be chewed or crushed. Concomitant intake of food does not influence the bioavailability.
Dosage should be adjusted to avoid bradycardia.
Hypertension: The recommended dosage in patients with mild to moderate hypertension is 50 mg Betaloc ZOK given once daily. In patients not responding to 50 mg the dose could be increased to 100-200 mg once daily and/or combined with other antihypertensive agents.
Angina pectoris: The recommended dosage is 100-200 mg Betaloc ZOK given once daily. If needed, Betaloc ZOK can be combined with other antianginal agents.
Cardiac arrhythmias: The recommended dosage is 100-200 mg Betaloc ZOK given once daily.
Prophylactic treatment after myocardial infarction: Long-term oral treatment with metoprolol in doses of 200 mg given once daily has been shown to reduce the risk of death (including sudden death), and to reduce the risk of reinfarction (also in patients with diabetes mellitus).
Functional heart disorders with palpitations: The recommended dosage is 100 mg once daily. If needed, the dose can be increased to 200 mg.
Migraine prophylaxis: The recommended dosage is 100-200 mg once daily.
Impaired renal function: Dose adjustment is not needed in patients with impaired renal function.
Impaired hepatic function: Dose adjustment is normally not needed in patients suffering from liver cirrhosis because metoprolol has a low protein binding (5-10%). When there are signs of serious impairment of liver function (e.g. shunt-operated patients) a dose reduction should be considered.
Elderly: Dose adjustment is not needed in the elderly.
Children: There is limited experience with Betaloc ZOK treatment in children.
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