Calciumfolinat-Ebewe

Calciumfolinat-Ebewe

calcium folinate

Manufacturer:

Sandoz

Distributor:

Zuellig Pharma

Marketer:

Novartis
Concise Prescribing Info
Contents
Ca folinate
Indications/Uses
Antidote to methotrexate. All indications of Ca folinate (or leucovorin Ca) including combination therapy of colorectal carcinoma w/ 5-FU. Amp soln can be used in local treatment of mouth ulcers.
Dosage/Direction for Use
6-12 mg/m2 for the 1st time 2-4 hr after the methotrexate infusion. Given at intervals of 3-6 hr over a total period of 72 hr.
Contraindications
Pernicious or other anaemia due to vit B12 deficiency.
Special Precautions
Possibility of allergic reactions.
Adverse Reactions
GI complaints at high doses. Haematological remissions w/ simultaneous progression of neurological disturbances.
Drug Interactions
Folic acid antagonists.
ATC Classification
V03AF03 - calcium folinate ; Belongs to the class of detoxifying agents used in antineoplastic treatment.
Presentation/Packing
Form
Calciumfolinat-Ebewe soln for inj 350 mg/35 mL
Packing/Price
1's
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