Cesoline-W

Cesoline-W

hydralazine

Manufacturer:

Central Poly Trading

Distributor:

Central Poly Trading
Concise Prescribing Info
Contents
Hydralazine HCl
Indications/Uses
Combination therapy in HTN & chronic CHF.
Dosage/Direction for Use
Adult Initially 10 mg qid for 2-4 days. May be increased to 25 mg qid. CHF 50-75 mg every 6-12 hr.
Administration
Should be taken with food.
Contraindications
Idiopathic SLE & related diseases. Severe tachycardia & heart failure w/ high cardiac output. Myocardial insufficiency due to mechanical obstruction. Isolated right ventricular heart failure due to pulmonary HTN. Dissecting aortic aneurysm.
Special Precautions
Gradual w/drawal is needed if drug needs to be stopped. Caution use in severe coronary insufficiency, SA node dysfunction, CNS depression. Prolonged treatment especially w/ doses >100 mg/day may provoke SLE-like syndrome mainly in slow acetylators. Periodic urine analysis & determination of anti-nuclear factors are recommended. Suspected or confirmed CAD. Recent MI. Renal impairment, hepatic dysfunction, cerebrovascular disease, surgery.
Adverse Reactions
SLE-like syndrome (arthralgia, joint swelling, fever), tachycardia, hypotension, nausea, haemolytic anaemia, agranulocytosis, hepatitis, glomerulonephritis, acute renal failure, anticholinergic effects (dry mouth, constipation), drowsiness, dizziness, pruritus, erythema.
Drug Interactions
BP-lowering effect may be potentiated by concurrent use of anesth, other antihypertensive agents, minor tranquilizers, TCAs. Decreased antihypertensive effect when used concomitantly w/ sympathomimetics. Administration shortly before or after diazoxide may give rise to marked hypotension.
ATC Classification
C02DB02 - hydralazine ; Belongs to the class of hydrazinophthalazine derivatives. Used in the treatment of hypertension.
Presentation/Packing
Form
Cesoline-W film-coated tab 10 mg
Packing/Price
50 × 10's
Form
Cesoline-W film-coated tab 25 mg
Packing/Price
50 × 10's
Form
Cesoline-W film-coated tab 50 mg
Packing/Price
50 × 10's
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