Central nervous system: Headache (27% to 34%).
Gastrointestinal: Abnormal stools (12% to 15%), diarrhea (12% to 19%).
Respiratory: Rhinitis (7% to 12%).
Miscellaneous: Infection (10% to 14%).
2% to 10%:
Cardiovascular: Peripheral edema (7% to 9%), palpitation (5% to 10%), tachycardia (4%).
Central nervous system: Dizziness (9% to 10%), vertigo (up to 3%).
Gastrointestinal: Dyspepsia (6%), nausea (6% to 7%), abdominal pain (4% to 5%), flatulence (2% to 3%).
Neuromuscular and skeletal: Back pain (6% to 7%), myalgia (2% to 3%).
Respiratory: Pharyngitis (7% to 10%), cough (3% to 4%).
<2% (Limited to important or life-threatening):
Agranulocytosis, anemia, aplastic anemia, asthma, atrial fibrillation, atrial flutter, blindness, blood pressure increased, bursitis, cardiac arrest, cerebral infarction/ischemia, cerebrovascular accident, chest pain, CHF, cholelithiasis, colitis, coronary stent thrombosis, cystitis, diabetes mellitus, duodenal ulcer, duodenitis, esophageal hemorrhage, esophagitis, extradural hematoma, gastrointestinal hemorrhage, gout, granulocytopenia, hemorrhage, hepatic dysfunction, hot flashes, hyperglycemia,
hypotension, interstitial pneumonia, intracranial hemorrhage, jaundice, leukopenia, myocardial infarction/ischemia, neuralgia, nodal arrhythmia, pain, periodontal abscess, peptic ulcer, pneumonia, polycythemia, postural hypotension, pulmonary hemorrhage, pruritus, QTc
prolongation, rectal hemorrhage, retinal hemorrhage, retroperitoneal hemorrhage, Stevens-Johnson syndrome, subcutaneous hemorrhage, subdural hematoma, supraventricular tachycardia, syncope, thrombocytopenia, thrombosis, torsade de pointes, uric acid increased, ventricular tachycardia.