Adults: Usual Dose: 250 mg twice daily for 7 days.
Severe Infections: 500 mg twice daily for 6-14 days.
Eradication of H. pylori: Recommended Dose: 500 mg 3 times a day for 14 days.
Renal Impairment: Dosage adjustments are required in patients with severe renal impairment.
Creatinine Clearance <30 mL/min: 250 mg once daily for mild to moderately severe infections and 250 mg twice daily in more severe infections.