Symptoms: Cases of overdose (2-3 times the prescribed dose for several weeks) have been reported. This results in hepatitis, which resolved without long-term consequences after a dose interruption. Single doses of up to 80 mg/kg in patients with iron-overloaded beta-thalassemia have been tolerated, with nausea and diarrhea noted. In healthy volunteers, single dosages of up to 40 mg/kg/day were tolerated.
Treatment: There is no specific antidote for deferasirox. In case of overdose, employ gastric lavage.