Use is not appropriate at any stage of delivery of infant. Determine cause in case of persistent vag or uterine bleeding after administration. Consider additional therapy w/ another uterotonic agent in case of persisting uterine hypotonia or atonia & excessive bleeding. Patients receiving large vol of IV fluids. Monitor early signs of drowsiness, listlessness & headache. Carefully monitor patients w/ eclampsia & pre-eclampsia. Migraine, asthma & CV disease or any state in which rapid addition to extracellular water may produce hazard for an already overburdened system. Contraindicated in pregnancy & should not be used for induction of labour. Lactation. Childn <12 yr.