Adults: The dose of ENDOMETRIN is 100 mg administered vaginally two or three times daily starting at oocyte retrieval and continuing for up to 10 weeks total duration (or 12 weeks of gestation).
For patients older than 40 years three times daily administration is recommended.
Elderly: No clinical data have been collected in patients over age 65.
Children: There is no experience in children as there is no relevant indication for use of ENDOMETRIN in children.
Use in special population: There is no experience with use of ENDOMETRIN in patients with impaired liver or renal function.
Administration: ENDOMETRIN is to be placed directly into the vagina by the applicator provided.
Unwrap the applicator.
Put one tablet in the space provided at the end of the applicator. The tablet should fit securely and not fall out.
The applicator with the tablet may be inserted into the vagina while you are standing, sitting, or when lying on your back with your knees bent. Gently insert the thin end of the applicator well into the vagina.
Push the plunger to release the tablet.
Remove the applicator and rinse it thoroughly in warm running water, wipe dry with a soft tissue and keep the applicator for subsequent use.