Endometrin Drug Interactions





Zuellig Pharma
Full Prescribing Info
Drug Interactions
Drugs known to induce the hepatic cytochrome-P450-3A4 system such as rifampicin, carbamazepine and also herbal products containing St. John's wort, (Hypericum perforatum) may increase the elimination of progesterone.
Ketoconazole and other inhibitors of cytochrome P450-3A4 may increase the bioavailability of progesterone.
The effect of concomitant vaginal products on the exposure of progesterone from ENDOMETRIN has not been assessed. ENDOMETRIN is not recommended for use with other vaginal products (such as antifungal products) as this may alter progesterone release and absorption from the vaginal tablet.
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