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Epadel S900

Epadel S900

icosapent ethyl

Manufacturer:

Catalent Japan

Distributor:

DKSH

Marketer:

Meiji
Concise Prescribing Info
Contents
Ethyl icosapentate
Indications/Uses
Hypertriglyceridemia. Adjunct in hypercholesterolemia w/ effective antihypercholesterolemia drug; to maximally tolerated statin therapy to reduce risk of MI, stroke, coronary revascularization & unstable angina requiring hospitalization in adults w/ elevated triglyceride (TG) levels (>200 mg/dL) & established CV disease or DM & ≥2 additional risk factors for CV disease; to diet in reducing TG levels in adults w/ severe hypertriglyceridemia (≥500 mg/dL).
Dosage/Direction for Use
Adult 1 sachet bid. Abnormalities in TG May increase dose to 1 sachet tid.
Administration
Should be taken with food: Take immediately after meals. Do not chew.
Contraindications
Hemorrhage eg, hemophilia, capillary fragility, GI ulcer, urinary tract & vitreous hemorrhage, hemoptysis.
Special Precautions
Discontinue if there is no response to treatment. Cerebral haemorrhage in patient w/ poorly controlled HTN. Patients menstruating; w/ bleeding tendency; scheduled to undergo surgery. Perform test to confirm hyperlipidemia; diet & exercise therapy or reduction of risk factors for ischemic heart disease eg, HTN & smoking, before initiating treatment. Regularly measure blood lipid level during treatment. Concomitant use w/ anticoagulants or antiplatelets. Pregnancy. Avoid breastfeeding during treatment. Low birth wt infants, infants, neonates. Childn.
Adverse Reactions
Rash, pruritus; anaemia; nausea, abdominal discomfort & pain, diarrhoea, heartburn; hepatic function disorder including increased AST (GOT), ALT (GPT), alkaline phosphatase, γ-glutamyl transpeptidase, LDH & bilirubin; increased creatine kinase (creatine phosphokinase).
Drug Interactions
Increased bleeding tendency w/ anticoagulants (eg, warfarin) & drugs that inhibit platelet aggregation (eg, aspirin, indomethacin, ticlopidine HCl, cilostazol).
MIMS Class
Dyslipidaemic Agents
ATC Classification
C10AX06 - omega-3-triglycerides incl. other esters and acids ; Belongs to the class of other lipid modifying agents.
Presentation/Packing
Form
Epadel S900 soft cap 900 mg
Packing/Price
84 × 45's
/thailand/image/info/epadel s900 soft cap 900 mg/900 mg (45 caps in unit-dose sachet)?id=badc55aa-eba5-4823-87c2-ad670086bfab
/thailand/image/info/epadel s900 soft cap 900 mg/900 mg?id=ee4f6330-791c-432f-adc8-ad670086bfab
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