Anemia associated w/ chronic renal failure including patients on dialysis (end-stage renal disease) & patients not on dialysis.
Dosage/Direction for Use
50 IU/kg IV 3 times/wk. Adjust dose & frequency depending on patient's response in increments of 25 IU/kg/wk IV at 4-wk intervals. If Hb increases >2 g/dL/wk, reduce treatment to 2 times/wk.
Contraindications
Hypersensitivity to mammalian cell-derived products or human albumin. History of pure red cell aplasia after treatment of erythropoietin, uncontrolled HTN.
Special Precautions
History of seizure disorder or underlying hematologic disease (eg, sickle cell anemia, myelodysplastic syndromes or hypercoagulable disorders). Porphyria. Evaluate Fe status including transferrin saturation & serum ferritin. Monitor renal function, fluid & electrolyte balance, hematocrit & BP. Perform CBC w/ differential & platelet count regularly. Pregnancy & lactation.
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 4000 IU59006f26-b81d-459b-b581-a4ec00fca69c.GIF)
