Eprex

Eprex Patient Counseling Information

epoetin alfa

Manufacturer:

Janssen-Cilag

Distributor:

DKSH
Full Prescribing Info
Patient Counseling Information
Injecting Eprex Under the Skin: At the start of therapy, Eprex may be injected by a medical or nursing staff. However, the doctor may decide if it is right for the patient to learn how to inject Eprex under the skin (SC). The patient will receive appropriate training to do this. Under no circumstance should the patient attempt to inject Eprex unless he/she has been trained to do so.
If Eprex is injected under the skin SC, the amount injected is not normally ≥1 mL in a single injection.
Eprex is given alone and not mixed with other liquids for injection.
Do not shake Eprex syringes or vials. Prolonged vigorous shaking may damage Eprex. If Eprex has been shaken vigorously, do not use it.
How to Inject Eprex using a Pre-Filled Syringe: The pre-filled syringes are fitted with the Protecs needle guard device to help prevent needle stick injuries after use.
Take a syringe out of the refrigerator. The liquid needs to come to room temperature. This usually takes between 15-30 min. Do not remove the syringe's needle cover while allowing it to reach room temperature.
Check the syringe. Make sure it is the right dose, not yet expired, not damaged and the liquid is clear and not frozen.
Choose the injection site. Good sites are at the top of the thigh and around the tummy (abdomen) but away from the navel. Vary the site from day to day.
Wash hands. Use an antiseptic swab on the injection site to disinfect it.
Hold the pre-filled syringe by the body of the syringe with the covered needle pointing upward.
Do not hold by the plunger head, plunger, needle guard wings or needle cover.
Do not pull back on the plunger at any time.
Do not remove the needle cover from the pre-filled syringe until Eprex is ready to be injected.
Take the cover off the syringe by holding the barrel and pulling the cover off carefully without twisting it. Do not push the plunger, touch the needle or shake the syringe.
Do not touch the needle activation clips to prevent prematurely covering the needle with the needle guard.
Pinch a fold of skin between the thumb and index finger. Do not squeeze it.
Push the needle in fully. The physician or nurse will show the patient how to do this.
Push the plunger with the thumb as far as it will go to inject all of the liquid. Push it slowly and evenly, keeping the skinfold pinched. Protecs needle guard will not activate unless the entire dose is given. A click may be heard when the Protecs needle guard has been activated.
When the plunger is pushed as far as it will go, take the needle out and let go of the skin.
Slowly take the thumb off the plunger. Allow the syringe to move up until the entire needle is covered by the needle guard.
When the needle is pulled out of the skin, there may be a little bleeding at the injection site. This is normal. An antiseptic swab may be pressed over the injection site for a few seconds after the injection.
Dispose the used syringe in a safe container.
Take only 1 dose of Eprex from each syringe. If any liquid remains in the syringe after an injection, the syringe should be properly disposed of, not reused (see How to Dispose of Eprex).
How to Inject Eprex using an Injection Prepared from a Vial: Only 1 dose of Eprex should be taken from each injection vial. Any fluid which remains should be thrown away.
Take a vial out of the refrigerator. The liquid needs to come to room temperature. This usually takes between 15-30 min.
Check the vial. Make sure it is the right dose, not yet expired, not damaged and the liquid is clear and not frozen.
Assemble the other items needed for the injection: Syringe, needle and antiseptic swabs.
Wash hands.
Remove the cap from the top of the vial but do not remove the rubber stopper. Clean the rubber stopper with an antiseptic swab.
Remove the needle cover from the syringe. Pull the syringe plunger out to fill the syringe with an amount of air equal to the amount of liquid prescribed by the physician.
Put the vial on a flat surface and push the syringe needle through the rubber stopper. Push the syringe plunger down to add the air into the vial.
Turn the vial and the syringe upside down. Pull on the syringe plunger to fill the syringe with the correct amount of liquid from the vial. It is important that the needle is always in the liquid in order to prevent air bubbles forming in the syringe.
Remove the syringe and needle from the vial. Hold the syringe with the needle pointing up to see if it has any air bubbles inside. If there are air bubbles, gently press the plunger until all of the air (but none of the liquid) has been removed.
Choose the injection site. Good sites are the top of the thigh and around the tummy (abdomen) but away from the navel. Vary the site from day to day.
Use an antiseptic swab on the injection site to disinfect it.
Pinch a fold of skin between the thumb and index finger. Do not squeeze it.
Push the syringe needle in fully. The physician or nurse will show the patient how to do this.
Push the plunger with the thumb as far as it will go to inject all of the liquid. Push it slowly and evenly, keeping the skinfold pinched.
When the plunger is pushed as far as it will go, take the needle out and let go of the skin.
Press an antiseptic swab over the injection site for a few seconds after the injection.
Dispose the used syringe in a safe container and dispose of the vial (see How to Dispose of Eprex).
Inform the physician or nurse immediately if too much Eprex has been injected.
If the patient forgot to use Eprex, make the next injection as soon as it is remembered. If the patient is within a day of the next injection, forget the missed one and carry on with the normal schedule. Do not double the dose of the injections.
How to Store Eprex: In hospital, vials and pre-filled syringes are stored unopened in a refrigerator between 2 and 8 degrees centigrade. If you are using Eprex at home, it is important that the vial or pre-filled syringe is stored in your refrigerator although not in the freezer compartment. Eprex should not be frozen. Allow the vial or pre-filled syringe to reach room temperature prior to using it. This usually takes between 15 and 30 minutes. Eprex vials or pre-filled syringes that are being used or about to be used can be kept at room temperature (not above 25°C) for a maximum single period of 7 days.
Vials and pre-filled syringes should be protected from light.
How to Dispose of Eprex: Medicines should not be disposed of via waste water or in household waste. Ask the pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.
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