Erimycin For Suspension

Erimycin For Suspension

Manufacturer:

Siam Bheasach

Distributor:

Siam Pharmaceutical

Marketer:

Siam Pharmaceutical
Concise Prescribing Info
Contents
Erythromycin ethylsuccinate
Indications/Uses
Resp tract & skin infections of mild to moderate severity. Prophylaxis of initial & recurrent rheumatic fever. Erythrasma, acute pelvic inflammatory disease, nongonococcal urethritis, Chlamydial infections, diphtheria, pertussis, Legionnaire disease, intestinal amoebiasis.
Dosage/Direction for Use
Adult 400 mg every 6 hr. Max: 4 g daily. Childn 30-50 mg/kg daily in 4 divided doses every 6 hr. Max: 3.2 g daily. Streptococcal infections Administer for at least 10 days. Community-acquired pneumonia w/ presumed mild atypical infection (M. pneumoniae, C. pneumoniae, C. trachomatis) or step-down therapy Childn & infants >3 mth 10 mg/kg/dose every 6 hr. Chlamydial infection Adult 800 mg qid for 7 days or 400 mg qid for 14 days if there is GI intolerance. Childn 50 mg/kg daily in 4 divided doses for 14 days. Pertussis 40-50 mg/kg/day in 4 divided doses for 5-14 days. Intestinal amoebiasis Adult 400 mg qid for 10-14 days. Childn 30-50 mg/kg/day in 4 divided doses for 10-14 days. Prophylaxis of recurrent rheumatic fever Adult 400 mg bid. Nongonococcal urethritis Adult 800 mg qid for 7 days. Legionnaire disease Adult 1.6-4 g daily in divided doses.
Administration
May be taken with or without food: May be taken w/ food to decrease GI upset. Do not give w/ milk or acidic beverages.
Contraindications
Hypersensitivity. Concomitant use w/ pimozide, cisapride, ergotamine or dihydroergotamine, terfenadine, astemizole, lovastatin or simvastatin.
Special Precautions
Impaired hepatic function w/ or w/o jaundice. Patients w/ prolonged QT interval, uncorrected hypokalemia or hypomagnesemia, clinical bradycardia or concurrent use of class IA or class III antiarrhythmic agents. Prolonged use may result in fungal or bacterial superinfection including Clostridium difficile-associated diarrhea (CDAD) & pseudomembranous colitis. Infantile hypertrophic pyloric stenosis (IHPS) in infants. Aggravate muscle weakness in patients w/ myasthenia gravis.
Adverse Reactions
GI disturbances, hepatotoxicity, skin reaction, weakness, hearing loss, allergic reactions.
Drug Interactions
Increased plasma conc w/ antifungal agent. Potentially serious adverse CV effects w/ astemizole, terfenadine, cisapride. Increase serum conc of diltiazem or verapamil, digoxin, carbamazepine, cyclosporine. Ergot alkaloids, benzodiazepines, theophylline, warfarin.
MIMS Class
ATC Classification
J01FA01 - erythromycin ; Belongs to the class of macrolides. Used in the systemic treatment of infections.
Presentation/Packing
Form
Erimycin For Suspension oral susp 200 mg/5 mL
Packing/Price
60 mL x 1's
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