Exelon Patch

Exelon Patch

rivastigmine

Manufacturer:

Novartis

Distributor:

Zuellig Pharma
Concise Prescribing Info
Contents
Rivastigmine
Indications/Uses
Mild to moderately severe dementia of the Alzheimer type; severe dementia of the Alzheimer's type; mild to moderately severe dementia associated w/ Parkinson's disease.
Dosage/Direction for Use
Mild to moderately severe dementia associated w/ Parkinson's disease Start w/ Exelon patch 5 once daily after a min of 4 wk. May be increased to Exelon patch 10. Individual responses may vary & some patients may derive additional benefit from higher doses. Subsequent increases to Exelon Patch 15 should always be based on good tolerability of the current dose & may be considered only after min of 4 wk of treatment at each dose level. Severe dementia of the Alzheimer's type Start w/ Exelon patch 5 once daily, may be increased to Exelon patch 10 & then to Exelon patch 15.
Contraindications
Known hypersensitivity to other carbamate derivatives. Previous history of application site reactions suggestive of allergic contact dermatitis w/ Exelon patch.
Special Precautions
Hepatic impairment. Carefully titrate & monitor patients w/ <50 kg body wt; patients w/ Alzheimer's disease wt loss. GI disorders may occur when initiating or increasing dose. Sick sinus syndrome or conduction defects (SA & AV block); active gastric or duodenal ulcers or predisposed to these condition when gastric acid secretions increased; predisposed to urinary obstruction & seizures; history of asthma or obstructive pulmonary disease. Discontinue if allergic contact dermatitis occurs. Do not remove old patch when putting a new one & use of multiple patches at 1 time. May affect ability to drive or operate machinery. Pregnancy & lactation.
Adverse Reactions
Nausea, fall, application site erythema.
Drug Interactions
May interfere anticholinergic activity of cholinomimetic drugs. May exaggerate effects of succinylcholine-type muscle relaxants.
ATC Classification
N06DA03 - rivastigmine ; Belongs to the class of anticholinesterases. Used in the management of dementia.
Presentation/Packing
Form
Exelon Patch 5 (transdermal patch 4.6 mg/24 hr)
Packing/Price
30 × 1's
Form
Exelon Patch 15 (transdermal patch 13.3 mg/24 hr)
Packing/Price
30 × 1's
Form
Exelon Patch 10 (transdermal patch 9.5 mg/24 hr)
Packing/Price
30 × 1's
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