Famvir

Famvir

famciclovir

Manufacturer:

Atnahs

Distributor:

DKSH
Concise Prescribing Info
Contents
Famciclovir
Indications/Uses
Herpes zoster &/or 1st & recurrent episodes of genital herpes in immunocompetent adults.
Dosage/Direction for Use
Adult Herpes zoster 250 mg tid for 7 days. Patients w/ renal impairment CrCl ≥40 mL/min 250 mg tid for 7 days, 20-39 mL/min 500 mg once daily for 7 days, <20 mL/min 250 mg once daily for 7 days. Hemodialysis patients 250 mg following each dialysis during 7 days. 1st episode of genital herpes 250 mg tid for 5 days. Patients w/ renal impairment CrCl ≥40 mL/min 250 mg tid for 5 days, 20-39 mL/min 250 mg bid for 5 days, <20 mL/min 250 mg once daily for 5 days. Hemodialysis patients 250 mg following each dialysis during 5 days. Recurrent episodes of genital herpes 125 mg bid for 5 days. Patients w/ renal impairment CrCl ≥20 mL/min 125 mg bid for 5 days, <20 mL/min 125 mg once daily for 5 days. Hemodialysis patients 125 mg following each dialysis during 5 days.
Administration
May be taken with or without food.
Contraindications
Hypersensitivity to famciclovir or penciclovir.
Special Precautions
Caution in patients w/ impaired renal function. Severe hepatic impairment. Avoid intercourse when symptoms are present & during initiation of treatment. Women of child-bearing potential. Pregnancy & lactation.
Adverse Reactions
Headache. Dizziness; vomiting, nausea, abdominal pain, diarrhea; abnormal liver function test; rash, pruritus. Serious skin reactions eg, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis, hypersensitivity vasculitis.
Drug Interactions
Increased plasma conc of penciclovir (active metabolite) w/ probenecid. Efficacy may be affected by raloxifene.
MIMS Class
Antivirals
ATC Classification
J05AB09 - famciclovir ; Belongs to the class of nucleosides and nucleotides excluding reverse transcriptase inhibitors. Used in the systemic treatment of viral infections.
Presentation/Packing
Form
Famvir FC tab 250 mg
Packing/Price
3 × 7's
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