Febuxostat - oral

Patient Medicine Information
Why do I need this medicine?
Febuxostat is used to lower the high levels of uric acid in the body.

Build-up of uric acid in your body can cause gout, gouty arthritis, kidney or urinary tract stones. This medicine is used to prevent or treat these conditions.

Febuxostat may also be used to treat or prevent high levels of uric acid in the blood that may occur during cancer treatment.
How do I take this medicine?
Take Febuxostat exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.

You may take this medicine with or without food. Try to take it at the same time each day.

Febuxostat must be taken regularly for it to be effective. Continue taking this medicine even when you feel better. Do not stop taking it unless instructed by the doctor.
What should I do if I have forgotten to take this medicine?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.

DO NOT double a dose under any circumstances.

If you often forget to take your medicine, let your doctor and pharmacist know.
When should I not use this medicine?
Do not take Febuxostat with mercaptopurine (certain medicine for cancer) or with azathioprine (medicine used in organ transplant or certain immune disorders).
What should I take note of while taking this medicine?
Inform your doctor if you have the following conditions:
  • history of an allergic reaction to allopurinol (other medicine for high uric acid level in the blood)
  • heart disease e.g. previous heart attack, heart failure
  • thyroid disease
  • kidney disease
  • liver disease
  • received an organ transplant
  • Lesch-Nyhan syndrome (a rare inherited disorder characterised by neurological or behavioural abnormalities and high levels of uric acid in the body)
Let your doctor know if you are pregnant or breastfeeding.

Keep your appointments with your doctor. Your doctor needs to monitor your condition and check your response to the medication regularly.
  • Routine tests (e.g. liver/kidney/heart function, uric acid levels) may be done while you are being treated with this medicine. Your doctor will advise you about how often you will need to have these tests.
  • Regular monitoring for signs of skin reactions or liver damage may also be needed.
What side effects could I experience?
Febuxostat may cause dizziness, drowsiness, blurred vision, and numbness or tingling sensations in the hands or feet. If affected, do not drive or take part in any activity in which you need to be alert or need to see clearly.

Other side effects include any of the following: headache, nausea, diarrhoea, joint pain, and swelling of the ankles, feet or hand.

Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:
  • rashes, breathlessness, swelling of the face, eyes or mouth
  • chest pain, irregular or abnormal heartbeat
  • yellowing of the skin or eyes, abdominal pain, dark coloured urine, tiredness
  • rashes with peeling of the skin or blistering of the lips, mouth or eyes accompanied by fever
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Can I take this with other medicines?
Do not take Febuxostat with mercaptopurine (certain medicine for cancer) or with azathioprine (medicine used in organ transplant or certain immune disorders).

Inform your doctor and pharmacist if you are taking theophylline (medicine for asthma).

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
What special dietary instructions should I follow?
In order to prevent future gout attacks, it is important to be mindful of your diet.

Avoid excessive alcohol intake. Drink plenty of water to keep hydrated.

Avoid foods high in purine, such as organ meat, seafood and oily fish. Other foods with purine content, such as meat, poultry, fish, may be eaten in moderation.

Eat a healthy, balanced diet low in highly processed foods and refined sugar (sugar that is commonly found in processed foods including soft drinks, candies, canned fruits).
How should I store this medicine?
Store in a cool, dry place away from the reach of children. Protect from light.

Medicines must not be used past the expiry date.
This information is independently developed by MIMS based on febuxostat - oral and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 MIMS. All rights reserved. Powered by MIMS.com
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