Feliz S

Feliz S

escitalopram

Manufacturer:

Torrent

Distributor:

Atlanta Medicare

Marketer:

Atlanta Medicare
Concise Prescribing Info
Contents
Escitalopram oxalate
Indications/Uses
Major depressive episodes. Generalized anxiety disorder.
Dosage/Direction for Use
Major depressive episodes 10 mg once daily. May be increased to a max of 20 mg daily. After symptoms resolve, treatment for at least 6 mth is required. Elderly Initially ½ of the usual recommended dose. Hepatic impairment Initially 5 mg daily for the first 2 wk of treatment. Generalized anxiety disorder 10 mg once daily. May be increased to a max of 20 mg daily. Treatment for 3 mth is recommended. Elderly Initially ½ of the usual recommended dose. Hepatic impairment Initially 5 mg daily for the first 2 wk of treatment.
Administration
May be taken with or without food.
Contraindications
Hypersensitivity to escitalopram or citalopram. Concomitant use w/ non-selective, irreversible MAOIs, reversible MAO-A inhibitors eg, moclobemide or the reversible non-selective MAOI linezolid, pimozide.
Special Precautions
Gradually w/draw treatment. Increased risk of suicidal thinking & behavior. Paradoxical anxiety. Discontinue if seizure or increase in seizure frequency (in patients w/ a previous diagnosis of epilepsy), serotonin syndrome or neuroleptic malignant syndrome occurs; patients entering a manic phase. Closely monitor patients w/ controlled epilepsy. History of mania/hypomania. Diabetes. History of suicide-related events, or those exhibiting a significant degree of suicidal ideation prior to initiation of treatment. Akathisia/psychomotor restlessness. Patients w/ cirrhosis or receiving drugs which may cause hyponatraemia; w/ known bleeding tendencies. Concomitant use w/ oral anticoagulants, drugs known to affect platelet function eg, atypical antipsychotics & phenothiazines, most TCAs, acetylsalicylic acid, NSAIDs, ticlopidine & dipyridamole; drugs w/ serotonergic effects eg, sumatriptan or other triptans, tramadol & tryptophan; St. John's wort (Hypericum perforatum). Electroconvulsive therapy. Pregnancy & lactation. Elderly.
Adverse Reactions
Insomnia, nausea, increased sweating, sexual dysfunction (ejaculation disorder), decreased libido, anorgasmia, fatigue & somnolence.
Drug Interactions
Risk of serotonin syndrome w/ irreversible non-selective MAOIs, reversible, selective MAO-A inhibitor eg, moclobemide, irreversible, selective MAO-B inhibitor eg, selegiline. Reversible, non-selective MAOI eg, linezolid. May lead to serotonin syndrome w/ serotonergics eg, tramadol, sumatriptan & other triptans. May lower seizure threshold w/ antidepressants (eg, tricyclics, SSRIs), neuroleptics (eg, phenothiazines, thioxanthenes & butyrophenones), mefloquine, bupropion & tramadol. Enhanced effects w/ lithium or tryptophan. Increased adverse reactions w/ herbal remedies containing St. John's wort (Hypericum perforatum). May alter anticoagulant effects w/ oral anticoagulants. Increased bleeding tendency w/ NSAIDs. Increased plasma conc w/ CYP2C19 inhibitors eg, omeprazole, cimetidine, esomeprazole, fluvoxamine, lansoprazole, ticlopidine. Drugs metabolised by CYP2D6 & w/ narrow therapeutic index eg, flecainide, propafenone & metoprolol or some CNS acting drugs mainly metabolized by CYP2D6 eg, desipramine, clomipramine & nortriptyline, risperidone, thioridazine & haloperidol.
ATC Classification
N06AB10 - escitalopram ; Belongs to the class of selective serotonin reuptake inhibitors. Used in the management of depression.
Presentation/Packing
Form
Feliz S FC tab 10 mg
Packing/Price
3 × 10's
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