Hypersensitivity to the active substance or to any of its excipients.
Pregnancy and lactation (see Precautions and Use in Pregnancy & Lactation).
Severe renal impairment.
Metabolic bone diseases other than primary osteoporosis (including hyperparathyroidism and Paget's disease of the bone).
Unexplained elevations of alkaline phosphatase.
Prior external beam or implant radiation therapy to the skeleton.
Patients with skeletal malignancies or bone metastases should be excluded from treatment with teriparatide.