Human Albumin 200 g/L Takeda

Human Albumin 200 g/L Takeda

human albumin




Zuellig Pharma
Concise Prescribing Info
Human albumin
Albumin replacement in major albumin deficiency due to: Hepatic cirrhosis, nephrotic syndrome, fluid loss into the extravascular compartment; oedema in patients w/ albumin deficiency; pre- & post-op treatment. Shock due to blood loss, burns w/ increased haematocrit (diluted to 5% soln w/ isotonic electrolyte &/or dextrose soln).
Dosage/Direction for Use
Individualized dose. Administer IV infusion at 1-2 mL/min. Pre & post-op treatment Adult 100-200 mL daily or diluted to 5%, depending on plasma vol & serum albumin level. Childn 1.5-3 mL/kg daily or diluted to a 5% soln. Hepatic cirrhosis Adult 100-200 mL daily. Infants & childn 1.5-3 mL/kg. Nephrotic syndrome Adult 200-400 mL daily, infused over 60-90 min. Infants & childn 3-6 mL/kg infused for 60-90 min. Oedema in patients w/ albumin deficiency Adult 100 mL. Childn 2 mL/kg. Fluid loss into the extravascular compartment Adult 50-200 mL. Childn 1-2 mL/kg. Initial dose should be infused over 5-15 min. Shock due to blood loss Adult 50-200 mL to be diluted 1:4 w/ isotonic electrolyte &/or dextrose soln. Childn 1-2 mL/kg diluted 1:4 w/ isotonic electrolyte &/or dextrose soln. Severe blood loss Initially 20 g infused rapidly at 5-15 min. Burns w/ increased hematocrit Adult 200-400 mL diluted 1:4 w/ isotonic electrolyte &/or dextrose soln. Childn 4 mL/kg diluted 1:4 w/ isotonic electrolyte &/or dextrose soln. In case of hypoalbuminemia Adult 50 mL bid. Childn 1 mL/kg bid.
Special Precautions
Monitor hemodynamics, electrolyte status & BP. Chronic renal insufficiency patients. Conditions where hypervolemia or hemodilution could have risk: Decompensated cardiac insufficiency, HTN, esophageal varices, pulmonary edema, hemorrhagic diathesis, severe anemia, renal & post-renal failure. Discontinue if clinical signs of CV overload (eg, headache, dyspnea, jugular vein congestion), increased BP, raised central venous pressure & pulmonary edema occurs; allergic or anaphylactic reaction occurs. Ensure adequate substitution of blood constituents (eg, coagulation factors, electrolytes, platelets & erythrocytes). Perform appropriate hemodynamic monitoring. Careful observation in injured or post-op patient of BP elevation after infusion. Patients on a controlled Na diet. Pregnancy & lactation. Ped patients.
ATC Classification
B05AA01 - albumin ; Belongs to the class of blood substitutes and plasma protein fractions. Used as blood substitutes.
Human Albumin 200 g/L Takeda inj 20 % w/v
50 mL x 1's
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