Hydralazine - oral

Patient Medicine Information
Why do I need this medicine?
Hydralazine is used together with other medicines to keep your blood pressure under control.

This medicine may also be used to treat other conditions such as heart failure.
How do I take this medicine?
Take Hydralazine exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.

Take it together with food or immediately after a meal. Try to take it at the same time each day.

Hydralazine must be taken regularly for it to be effective. Continue taking this medicine even when you feel better. Do not stop taking it unless instructed by the doctor.
What should I do if I have forgotten to take this medicine?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.

DO NOT double a dose under any circumstances.

If you often forget to take your medicine, let your doctor and pharmacist know.
When should I not use this medicine?
Alert your doctor if you have any of the following:
  • systemic lupus erythematosus (SLE) (an autoimmune disease that causes inflammation)
  • heart disease caused by an overactive thyroid or by high blood pressure in the lungs
  • aortic aneurysm (weakness in the aortic wall)
  • coronary artery disease (disorder of the blood vessels of the heart)
  • mitral valve rheumatic heart disease (a heart disease caused by rheumatic fever)
  • porphyria (a rare blood disorder)
  • other heart diseases e.g. narrowing of the heart valves or blood vessels, rapid heartbeat
as Hydralazine may not be suitable for you.
What should I take note of while taking this medicine?
Inform your doctor if you have the following conditions:
  • cerebrovascular disease (disorder of blood vessels in the brain)
  • slow acetylator (a state in which the body takes a longer time to handle medicines)
  • liver disease
  • kidney disease
Let your doctor know if you are pregnant or breastfeeding.

If you are going to have an operation, including minor surgery and dental work, inform your doctor or dentist that you are taking Hydralazine.

Why is it important to keep my appointments with the doctor?

Keep your appointments with your doctor. Your doctor needs to monitor your condition and check your response to the medication regularly.
  • Routine tests (e.g. blood tests, urine analysis) may be done before treatment or while you are being treated with this medicine.
  • Your blood pressure may fall to unsafe levels without you noticing it. Monitor your blood pressure and heart rate during treatment.
Your doctor will advise you about how often you need to have these tests.

What lifestyle changes can I make to improve my blood pressure?

Regular exercise and eating a healthy diet will help control your blood pressure and improve your overall health. Engage in physical activity like walking for at least 30 to 60 minutes on most days of the week. If you have not exercised for a long time, start with light exercises such as slow walks. Speak to your doctor about what type of exercise would be suitable for you. Follow a healthy diet plan by eating more fruits, vegetables, whole grains and low-fat dairy products and reduce your intake of foods high in saturated fat, cholesterol and sodium. Cutting down on deep-fried foods and using less salt when cooking can kick-start your healthy diet.

If you smoke, you should try to quit. Smoking is harmful to your blood pressure, heart and overall health. Speak to your doctor or pharmacist about ways to stop your smoking habit.
What side effects could I experience?
Hydralazine may cause dizziness. If affected, do not drive or take part in any activity in which you need to be alert.

Other side effects include any of the following: headache, diarrhoea, nausea, vomiting, constipation, joint pain and swelling, muscle pain, loss of appetite, redness of the skin, reduced amount of urine, swelling of the ankles, feet or legs, and rapid or fast heartbeat.

This medicine may cause your blood pressure to fall suddenly when you get up from a sitting or lying down position and you may feel giddy. To minimise this problem, stand up slowly.

Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Can I take this with other medicines?
Inform your doctor and pharmacist if you are taking any of the following:
  • other medicines for high blood pressure e.g. amlodipine, enalapril
  • NSAIDs (medicines for pain and inflammation) e.g. ibuprofen, diclofenac
  • medicines for depression e.g. imipramine, clomipramine
  • anti-inflammatory medicines e.g. hydrocortisone, prednisolone
  • birth control pills e.g. oestrogen
  • diazoxide (medicine for low blood sugar)
This list does not include all medicines that may interact with Hydralazine.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
What special dietary instructions should I follow?
Avoid alcohol.
How should I store this medicine?
Store in a cool dry place away from reach of children.

Medicines must not be kept past the expiry date.
This information is independently developed by MIMS based on hydralazine - oral and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 MIMS. All rights reserved. Powered by MIMS.com
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