Sriprasit Pharma


SPS Medical
Concise Prescribing Info
Bisoprolol fumarate
Listed in Dosage.
Dosage/Direction for Use
Essential HTN, angina pectoris 5 mg. May increase to 10 mg if not adequate. CHF Initially 1.25 mg/day for 1 wk, gradually increase to 2.5 mg/day for 1 wk then 3.75 mg/day for 1 wk then 5 mg/day for the following 4 wk & 7.5 mg/day for the following 4 wk. Maintenance: 10 mg/day. All doses to be taken once daily.
May be taken with or without food.
Untreated myocardial failure, cardiogenic shock, AV block grade II & III, sick-sinus syndrome, SA block, bradycardia (<50 beats/min), bronchial asthma, hypotension, advanced stages of peripheral circulatory disturbance, pheochromocytoma w/o concomitant α-adrenoceptor blocker therapy. Pregnancy, lactation. Childn.
Special Precautions
Diabetics. Fluctuating blood sugar levels, during prolonged periods of fasting; acidosis. Prior operation as cardiac output may be impaired under anesth. Elderly >80 yr.
Adverse Reactions
Rarely, GI disturbances, skin reactions, decreased BP, slow pulse rate, cold extremities, muscle weakness/cramp, reduced lacrimation. May aggravate intermittent claudication & Raynaud's phenomenon, intensify myocardial failure, increase airway resistance, mask sign of low sugar levels. Fatigue, dizziness, slight headache, perspiration, sleep disturbances, vivid dreams, depressive moods.
Drug Interactions
Reserpine, α-methyldopa, Ca antagonist of the verapamil- & diltiazem-type, antiarrhthymics, insulin or oral blood sugar-lowering drugs.
MIMS Class
ATC Classification
C07AB07 - bisoprolol ; Belongs to the class of selective beta-blocking agents. Used in the treatment of cardiovascular diseases.
Hypercor tab 5 mg
10 × 10's
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