Hysone

Hysone Overdosage

hydrocortisone

Manufacturer:

GPO

Distributor:

GPO
Full Prescribing Info
Overdosage
Symptoms: Overdosage may cause nausea and vomiting, sodium and water retention, hyperglycaemia and occasional gastrointestinal bleeding. Treatment need only be symptomatic although cimetidine (200-400 mg by slow intravenous injection every 6 hours) or ranitidine (50 mg by slow intravenous injection every 6 hours) may be administered to prevent gastrointestinal bleeding.
Cushingoid changes: Cushingoid changes from continued use of large doses resulting in moonface, central obesity, striae, hirsutism, acne, ecchymoses, hypertension, osteoporosis, myopathy, sexual dysfunction, diabetes, hyperlipidemia, peptic ulcer, increased susceptibility to infection and electrolyte and fluid imbalance. Reports of acute toxicity or death are rare.
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