Increased risk of hyperkalemia w/ K salts/supplements, clotrimazole, ACE inhibitors & K-sparing diuretics. Increased effects of amiodarone, bosentan, dapsone, fluoxetine, glimepiride, glipizide, losartan, montelukast, nateglinide, paclitaxel, phenytoin, pioglitazone, repaglinide, rosiglitazone, warfarin, zafirlukast & other CYP2C8 & CYP2C9 substrates, & CYP2D6 (weak) & CYP3A4 (weak). Dong quai. HTN may worsen w/ ephedra, yohimbine, ginseng. Increased antihypertensive effect w/ garlic.