Japrolox

Japrolox

loxoprofen

Manufacturer:

Daiichi Sankyo

Distributor:

Zuellig Pharma

Marketer:

Daiichi Sankyo
Concise Prescribing Info
Contents
Anhydrous loxoprofen Na
Indications/Uses
Chronic articular rheumatism, OA, lumbago, periarthritis of the shoulder & shoulder-arm-neck syndrome. Relieves pain & inflammation after operation, trauma & tooth extraction.
Dosage/Direction for Use
Adult 60 mg tid. Single dose: 60-120 mg.
Administration
Should be taken with food.
Contraindications
History of hypersensitivity. Patients w/ peptic ulcers; severe blood disorders; severe hepatic function disorders; severe renal impairment; severe cardiac function failure. History of aspirin-induced asthma. Late stages of pregnancy.
Special Precautions
History of hypersensitivity. Cardiac dysfunction, bronchial asthma, ulcerative colitis, Crohn's disease. Patients w/ history of peptic ulcers or associated w/ chronic use of NSAIDs; blood disorders; hepatic function disorder; renal impairment. Periodic laboratory exam should be followed for long-term use. Appropriate antibiotic should be used in combination to treat inflammation due to infection. Concomitant use w/ other anti-inflammatory-analgesic agents. Temporary sterility in women receiving long-term therapy. Late stages of pregnancy. Lactation. Elderly.
Adverse Reactions
GI symptoms eg, stomach discomfort, abdominal pain, nausea &/or vomiting, anorexia; edema; rash; urticarial; sleepiness.
Drug Interactions
May enhance anticoagulant effect of coumarin anticoagulants (eg, warfarin). Increased risk of bleeding w/ factor Xa inhibitor. May enhance hypoglycemic effect of sulfonylurea hypoglycemic agents (eg, tolbutamide). May enhance convulsant effect of new quinolone antimicrobial agents (eg, levofloxacin hydrate). May increase plasma conc of methotrexate & lithium. May reduce diuretic-antihypertensive effects of thiazide diuretics (eg, hydrochlorothiazide). May reduce antihypertensive effects of antihypertensive drugs (eg, ACE inhibitors, angiotensin II receptor antagonists).
ATC Classification
M01AE - Propionic acid derivatives ; Used in the treatment of inflammation and rheumatism.
Presentation/Packing
Form
Japrolox tab 60 mg
Packing/Price
20's
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