Pregnancy: Category C.
The following symptoms may occur in the neonate after maternal SSRI/SNRI use in later stages of pregnancy: respiratory distress, cyanosis, apnea, seizures, temperature instability or fever, feeding difficulty, dehydration, excessive weight loss, vomiting, hypoglycaemia, hypotonia, hypertonia, hyperreflexia, tremor, jitteriness, irritability, and constant crying. These symptoms could be due to either serotonergic effects or discontinuation symptoms.
Lactation: Escitalopram is distributed into human milk. Nursing infants should be observed for adverse reactions when escitalopram is administered to a nursing woman because of the serious adverse effects e.g., excessive somnolence, decreased feeding, weight loss.