Letrozole Alvogen

Letrozole Alvogen

letrozole

Manufacturer:

Alvogen

Distributor:

Zuellig Pharma
Concise Prescribing Info
Contents
Letrozole
Indications/Uses
Adjuvant treatment of postmenopausal women w/ hormone receptor positive early breast cancer; extended adjuvant treatment of early breast cancer in postmenopausal women who have received prior standard adjuvant tamoxifen therapy for 5 yr. 1st-line treatment in postmenopausal women w/ hormone-dependent advanced breast cancer. Advanced breast cancer in women w/ natural or artificially induced postmenopausal status after relapse or disease progression, who have previously been treated w/ anti-oestrogens.
Dosage/Direction for Use
Administration
May be taken with or without food.
Contraindications
Hypersensitivity. Premenopausal endocrine status. Pregnancy & lactation.
Special Precautions
Cirrhosis, severe hepatic dysfunction. May affect ability to drive or use machinery. Childn. Elderly.
Adverse Reactions
Increased sweating; arthralgia; hot flushes, fatigue including asthenia. Anorexia, increased appetite, hypercholesterolaemia; depression; headache, dizziness; palpitation; nausea, vomiting, dyspepsia, constipation, diarrhoea; alopecia, rash including erythematous, maculopapular, psoriasis, vesicular rash; arthralgia, myalgia, bone pain & fractures, osteoporosis, arthritis; malaise, peripheral oedema, chest pain; increased wt, hyperbilirubinemia, jaundice, cough.
Drug Interactions
MIMS Class
Cancer Hormone Therapy
ATC Classification
L02BG04 - letrozole ; Belongs to the class of enzyme inhibitors. Used in treatment of neoplastic diseases.
Presentation/Packing
Form
Letrozole Alvogen FC tab 2.5 mg
Packing/Price
30's
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